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Job Title: Director, I&I and Rare Disease, Pipeline HEOR
Company Name: Pfizer
Location: Collegeville, PA
Position Type: Full Time
Post Date: 11/14/2020
Expire Date: 02/01/2021
Job Categories: Biotechnology and Pharmaceutical, Finance/Economics, Government and Policy, Healthcare, Other, Healthcare, Practitioner and Technician, Legal, Manufacturing and Production, Research & Development, Medical, Writing/Authoring
Job Description
Director, I&I and Rare Disease, Pipeline HEOR

Successful global market access is fundamental to the achievement of Pfizer's commercial objectives in the evolving, complex pharmaceutical payer environment, which must begin in early development. The Immunology and Inflammation (I&I) and Rare Disease (RD) business units within Pfizer have a robust pipeline of products within medical dermatology, rheumatology, and gastroenterology (I&I) and various rare diseases (RD) in: hematology, cardiology, neuromuscular, metabolic and endocrine, including several gene therapy assets across these TAs .

The HEOR Director, I&I and RD will lead the execution of HEOR and Real-World Evidence (RWE) and Patient-Centered Outcomes Assessments (PCOA) and evidence development plans for the therapeutic areas of Rheumatology, Dermatology and various Rare Diseases. Diseases areas of interest include Dermatomyositis, Systemic Lupus Erythematosus, Rheumatoid Arthritis in I&I and Wilson's Disease and Achondroplasia in RD (amongst potential others). Distribution of work effort will be roughly 50%/50% between I&I and RD, but may evolve over time, depending on business needs. The role is vital to ensure optimal evidence generation occurs in support of reimbursement and access needs for many indications, including those which may receive breakthrough designation.

This role directly impacts the ability to achieve business objectives on a global basis by leading the execution of evidence generation needs that are essential to achieve optimal global patient access by demonstrating the value of our products. To achieve this, the Director will collaborate cross-functionally to ensure there is a single and coordinated view on strategy and delivery for PHI to the I&I and RD business units.

HEOR takes a global business-wide perspective and must adopt a leadership position on strategic questions with respect to patient and payer value and evidentiary needs for access and outcomes required of assets in development. The Director must have a high degree of technical expertise with an execution mindset and employ a patient and payer-centric mindset to work closely in an aligned fashion with various partner and stakeholder groups. This will ensure there is a single and coordinated view on strategy to provide timely delivery of PHI outputs to inform key business decisions.


+ Innovation, Leadership and Strategic partnership on HEOR, RWE & PCOA strategy in support of pipeline product(s) value assessments toward clinical development, senior funding decisions and payer value proposition development.

+ Implement and incorporate humanistic and economic endpoints into clinical trials across all phases of product development to build comprehensive trial-based evidence in line with overall medical strategy for the assets and to ensure global reimbursement and access requirements.

+ Execution of HEOR studies (including RWE studies, registries, non-interventional studies, PRO qualitative and/or quantitative development, registries, etc.) that are compliant with Pfizer standard operating procedures and are supportive of asset value proposition.

+ Align with asset lead and incorporate input from local country/regional Health & Value teams on evidence needs, HTA interactions and payer requirements for optimal reimbursement.

+ Assist/lead the development of clinical development plans (CDP) briefing documents for regulatory and payer advice and prelaunch deliverables such as early global value dossiers (GVDs), evidence blueprints, economic models, and innovative tools to successfully support global launch, reimbursement and access requirements in conjunction with the regions/countries.

+ Identify and develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community settings to support asset strategies.

+ Lead the development of appropriate dissemination plans and communication via publications, conference presentations, or other means.

+ Work efficiently and collaboratively in a highly matrixed team

+ Execute projects as per Operating Plans or newly identified priorities and manage pipeline budget for those projects.


Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

+ Minimum Master's degree (MSc, MPH) in health services research, public health, epidemiology, or health economics or Pharm D with 5+ years' experience or a Doctoral degree (PhD, DrPH, ScD, PharmD with Fellowship) with 3+ years' experience in health services research, public health, epidemiology, or health economics.

+ Strong methodological skills (study design, data analysis and interpretation) in clinical trials, epidemiology, or health services research is required

+ Strong working knowledge of the technical and methodological aspects of clinical trials including regulatory requirements for PROs supporting label claims, best practices for ePRO/paper administration, real world evidence studies, registries and observational study design and implementation.

+ Capable of independently managing real world evidence studies, observational studies, and PRO development

+ In depth understanding of Pharmacoeconomics, Health-related Quality of Life and PRO development

+ Excellent interpersonal and active listening skills, ability to work in a highly matrix team environment, and an "execution mindset" focused on getting things done quickly and simply is required

+ Strong customer-orientation; an ability to see issues from the point of view of others.

+ Intellectual curiosity and ability to spot trends/ patterns

+ Demonstrated ability to manage multiple projects (multitask) involving complex processes, significant budget, competing deadlines and rapidly shifting priorities in a compliant manner

+ Excellent oral and written English communication skills required

+ Strong project management abilities (contracting, budgeting, vendor management) essential.


+ Demonstration of Courage, Excellence, Equity, and Joy attributes

+ Knowledge and experience in the RD and/or I&I therapeutic area and/or the pipeline and development space is a plus

+ Experience in the pharmaceutical industry.

+ Experience with US commercial/governmental payers, HTA organizations such as NICE, G-Ba, HAS, AIFA, SMC, PBAC, and regulatory agencies such as US FDA and EMA is desirable

+ Proven ability to develop strong partnerships across functions.

+ Executive presence and ability to interact effectively with all levels of the organization.

+ Outstanding writing and presentation skills

+ Ability to work successfully and cooperatively with colleagues across multiple cultures and time-zones.

+ Change to rare Diseases within rare hematology, rare cardiology, rare neuromuscular and rare metabolic and endocrine, including several gene therapy assets across these Rare TAs

**Other Job Details:**

Last Date to Apply for Job: January 3rd, 2021

Additional Location Information: New York, NY; Collegeville, PA; US - Remote


**Sunshine Act**

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

**EEO & Employment Eligibility**

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

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